Table 2 presents the prevalence and odds ratios for offspring lifetime alcohol dependence by specific combinations of parental divorce and maternal-paternal alcohol problems. Parental divorce and maternal (AOR = 2.49) or paternal (AOR = 2.13) only alcohol problems more than doubled the likelihood and parental divorce and both maternal and paternal alcohol problems more than tripled the likelihood (AOR = 3.25) for offspring lifetime alcohol dependence.