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Chunk #29 — Results — xQTL-weighted GWAS for gene discovery efforts

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An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome.
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= w1/w0 > 1 (see Supplementary Information for s selection). Consistent with the standard GWAS convention, significance was declared at p < 5x10−8. To not over-count the number of significant hits due to correlations between SNPs, we applied PLINK1.945 on the 1000 Genomes phase 1 data19 to remove SNPs among the significant hits that are in linkage disequilibrium with one other (r2<0.2).