improvement in BD symptoms 4 hours following cannabis use [126]; however, this only reflects an acute profile of cannabis use in BD. There are additional studies that suggest no statistically significant relationship between cannabis and BD outcomes [73, 121]. Moreover, there have been no studies to investigate any therapeutic relationship between cannabinoids and BD. Further research is necessary to better understand the nature of the relationship between cannabis and BD, but thus far the current literature indicates that there are more harmful consequences compared to benefits associated with long-term cannabis use in BD symptomatology and disease progression.
