The experiments were conducted by the Neuroelectrical Imaging and Brain Computer Interface laboratory (NEILab) at the Scientific Institute for Research, Hospitalization and Health Care, "Fondazione Santa Lucia" in Rome (Italy) and by the Biomedical Functional Imaging and Neuroengineering Laboratory at the University of Minnesota in Minneapolis (USA). All the subjects involved in the experiment were recruited by advertisement. Written informed consent was obtained from each subject after the explanation of the study, which was approved by the local institutional ethics committee of the Scientific Institute for Research, Hospitalization and Health Care, "Fondazione Santa Lucia" in Rome and by the Institutional Review Board of the University of Minnesota. Fifty-two voluntary and healthy subjects (age ranging from 23 to 33 years) participated in our experiment. They had no history of neurological or psychiatric disorders and they were free from medications, alcohol, or drug abuse. In the experimental setup, each of the 26 couples of subjects played the iterated Prisoner's Dilemma game of at least 200 trials. Every round, or trial, players were asked to choose either to cooperate (C) or defect (D)