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Chunk #35 — DISCUSSION — 18q23, Neural Connectivity and Development

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A genome-wide association study of interhemispheric theta EEG coherence: implications for neural connectivity and alcohol use behavior.
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We also investigated the association of rs12954372 with developmental trajectories of parietal-occipital EEG theta coherence in the COGA adolescent/young adult subsample to further our understanding of the developmental influences of salient genetic risk factors emerging from the coherence GWASs and their connection to alcohol use behavior. Interestingly, significant effects were only observed in females and were driven by associations observed after age 18 (Supplemental Figure 2).