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Chunk #29 — Discussion

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The structure of genetic and environmental risk factors for syndromal and subsyndromal common DSM-IV axis I and all axis II disorders.
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First, we replicated and extended the results of our earlier multivariate twin analysis, which included only seven disorders but clearly identified genetic internalizing and externalizing factors (13). The present study provides further support for the importance and generalizability of the internalizing and externalizing genetic dimensions of risk for common psychiatric disorders. While we identified separate internalizing and externalizing factors for axis I and II disorders, they were moderately intercorrelated.