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Chunk #49 — EROs and Alcoholism — EROs as Endophenotypes

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Event-Related Oscillations in Alcoholism Research: A Review.
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In summary, it can be said that the genetic underpinnings of evoked oscillations are likely to stem from regulatory genes which control the neurochemical processes of the brain, thereby influencing neural function. The major neurochemical substrates contributing to theta and delta rhythms and P3 has been suggested to be strongly glutamatergic, with strong modulatory influences from both cholinergic and GABAergic sources that elicit excitatory and inhibitory post-synaptic potentials, and indirect system interactions and contributions from the serotonergic, dopaminergic and noradrenergic systems [182,216].