Cases satisfied DSM-IV or ICD-10 criteria for SCZ and were broadly representative of clinical cases in contact with psychiatric services. DNA was extracted from whole blood, with approval from institutional review boards. CNVs were identified using the Birdseye package15 and analysed using PLINK v1.0314. See the Supplementary Information for detail. A list of all CNVs passing quality control is available at http://pngu.mgh.harvard.edu/isc/
