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Chunk #27 — Discussion — Implications for DSM-V — 2. Tolerance and Larger/Longer do not have consistent severity signals across samples

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Toward DSM-V: an item response theory analysis of the diagnostic process for DSM-IV alcohol abuse and dependence in adolescents.
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These findings should be studied further. If this phenomenon represents a biological difference 39 and those at greatest risk for serious alcohol dependence are less likely to develop these symptoms, then they should be reconsidered. If this phenomenon reflects differential interpretation of the questions, then the questions may need rewording.