Increases in state cigarette prices and restrictions on indoor smoking (SFA policies) were significantly associated with decreases in state per capita alcohol consumption during 1980–2009. The joint effects of the policies were significantly associated with reductions in consumption of total alcohol and of beer and spirits, but not wine. A 10% increase in cigarette price was associated with a 0.83% decrease in per capita total alcohol consumption and a 1.06% decrease in beer consumption. A one point increase in SFA policy score was associated with a 1.1% decrease in per capita total alcohol consumption, a 0.7% decrease in beer consumption, a 1.9% reduction in per capita spirits consumption.