The Alcohol Use Disorder and Associated Disabilities Interview Schedule – DSM-IV Version (AUDADIS-IV) was administered to NESARC participants to measure DSM-IV alcohol dependence (Grant et al., 2003). This fully structured instrument was specifically designed for experienced lay interviewers. Computer diagnostic programs implemented the DSM-IV criteria for diagnosing alcohol abuse and dependence using AUDADIS-IV data. Extensive AUDADIS-IV questions covered DSM-IV criteria for dependence. Consistent with DSM-IV, lifetime diagnoses of alcohol dependence required 3 or more of the 7 DSM-IV dependence criteria within a 12-month period. Test-retest reliability of AUDADIS-IV alcohol dependence diagnoses ranges from good to excellent (κ = 0.70–0.84). Many types of validation studies, including psychiatrist reappraisal of AUDADIS-IV alcohol dependence diagnoses (Canino et al., 1999), have shown its validity to be good to excellent, as described in detail elsewhere (Grant et al., 2004; Hasin and Grant, 2004).
