parameters estimated. Paths that were not significant were dropped from the model. The significance of paths with larger loadings was confirmed with calculation of CIs. A saturated trivariate Cholesky (ie, MDD, low-risk trauma, and high-risk trauma) was created for supplementary analyses of cohort II twin data (see eTables 5 and 6 and eFigure 2), and pathways were then dropped as described previously herein to determine the most parsimonious model.
