four located near the ACN9 gene, which codes for a mitochondrial intermembrane protein of gluconeogenesis (Dick et al., 2008). Investigation of mitochondrial abnormalities in patient derived neurons containing these SNPs is a potential avenue of research. Additionally, patient-derived liver cells can be generated from hiPSCs (Pashos et al., 2017; Warren et al., 2017) and these may be valuable for studying AUD-related variants linked with alcohol metabolism.
