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Chunk #6 — MATERIALS AND METHODS — Procedure — Cue-Exposure Paradigm

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Alcohol sensitizes cerebral responses to the odors of alcoholic drinks: an fMRI study.
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Before imaging, subjects were familiarized with the odorants used during scanning by presenting the odorants in synchrony with representative images as displayed on a computer screen (e.g., beer odor presented with an appealing photograph of a frosted mug of beer). Prior to this cue-exposure and after each stimulus class (AO, NApO, ApCO), subjects answered questions from the Alcohol Urge Questionnaire (AUQ; Bohn et al., 1995) to obtain a baseline rating of desire to drink. Subjects also rated mood on the same visual-analogue scale as used for the AUQ (i.e., range 1–7) to the following prompts: “I am depressed, angry, worried or frustrated” and “I am happy, joyful or pleased.” As with the AUQ, ‘1’ represented “Strongly Disagree” and ‘7’ represented “Strongly Agree.”