Decreased cortical thickness of the inferior parietal cortex was present in adult patients with OCD compared to healthy controls, but at a less stringent significance threshold (Cohen’s d≈ −0.14; p <0.01, uncorrected). The meta-analysis did show significant widespread effects of medication on cortical thickness and a lower surface area of the transverse temporal cortex in adult OCD patients. The pediatric meta-analysis, also on a less stringent significance threshold (Cohen’s d≈ −0.31; p <0.05, uncorrected), showed decreased cortical thickness of the inferior and superior parietal cortex in children with OCD. In addition, field strength did not significantly explain the effect size estimates of cortical thickness or surface area differences in adult and pediatric OCD patients compared to controls (Supplementary Information SI3)
