The PhenX investigators are currently collaborating with administrators of the database of Genotypes and Phenotypes (dbGaP) (8) (http://www.ncbi.nlm.nih.gov/gap/), the Public Population Project in Genomics (P3G) (25) (http://www.p3g.org/), the Data Schema and Harmonization Platform for Epidemiological Research (DataSHaPER) (26) (http://www.datashaper.org/), and the National Library of Medicine (http://www.nlm.nih.gov/). This work is focused on developing a consistent rule set for mapping PhenX measures to dbGaP study variables and DataSHaPER measures and variables. The plan is to highlight PhenX measures in dbGaP and DataSHaPER. The value of this approach is that investigators who visit the dbGaP or DataSHaPER site will be able to readily identify PhenX measures in these resources, thus facilitating data-sharing and data harmonization. In addition, researchers may be able to identify opportunities to extend studies to include data and samples associated with P3G biorepositories. The PhenX investigators are working collaboratively with the National Library of Medicine to ensure that PhenX is aligned with NIH bioinformatics efforts such as Logical Observation Identifiers Names and Codes (27, 28). They are also collaborating with the Electronic Medical Records and Genomics consortium (https://www.mc.vanderbilt.edu/) to facilitate sharing of data captured in electronic medical records.
