These tools have been implemented in a variety of technical platforms. For example, WebGestalt has a well known web server (2), GSEA is known for its stand-alone application (9), Enrichr, in addition to web service, also has an R package (1). Other tools serve its users across a variety of technical platforms. For example, g:Profiler serves its users via a web client and API, Python and R packages, and is available as a tool for Galaxy platform (10).