Pairs of related individuals within the UK Biobank cohort form networks of related individuals. In most cases, these are of size two, but there are also many groups of size three or larger in the cohort (Fig. 3b), even when restricting to second-degree relatives or closer relative pairs. By considering the relationship types and the age and sex of the individuals within each family group, we identified 1,066 sets of trios (two parents and an offspring), which comprise 1,029 unique sets of parents and 37 quartets (two parents and two children).