eQTL variants for whole blood that were fine-mapped using CAVIAR66 were downloaded from the GTEx v8 website (https://storage.googleapis.com/gtex_analysis_v8/single_tissue_qtl_data/GTEx_v8_finemapping_CAVIAR.tar)51. For each fine-mapped eQTL overlapping a peak that was linked to a gene in our analysis we counted the number of times the eQTL-associated gene was the same as the linked gene. Cases where multiple fine-mapped eQTLs associated with the same gene overlapped the same peak were treated as a single variant. To find the expected overlap based on random chance, we selected a set of peaks for each gene at random from the peaks within 500 kb of the gene TSS, with the number of peaks selected equal to the number of linked peaks for that gene. We then repeated the same eQTL overlap analysis using the randomized link set, as described above.
