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Chunk #24 — INTERPRETATIONS OF PAC STRENGTH

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Alcohol use disorder is associated with increases in frontocentral phase-amplitude coupling strength during resting state.
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It is generally understood that the oscillatory dynamics of the brain captured by neuroelectric recordings reflect the coordinated interactions between groups of neurons across multiple temporal and spatial scales (Buzsáki, 2006; van Bree et al., 2025). Neurophysiological interpretations of PAC strength may benefit from comparisons with EEG coherence as they both represent measurements of these oscillatory dynamics.