paperKB
coga / coga-kb
Help
Sign in

Chunk #7 — Methods — Genetic correlations

Source
Parsing genetically influenced risk pathways: genetic loci impact problematic alcohol use via externalizing and specific risk.
Embedded
yes

Text

We estimated genetic correlations between EXT, ALCP-specific, ALCP-total and 99 preregistered phenotypes, again using GenomicSEM. A full list of the genetic correlations is available in Supplementary Table 2. Genetic correlations allowed us to examine how patterns of associations differed across EXT, ALCP-total, and ALCP-specific. In determining which genetic correlations to compare, we limited results to those which were significantly associated with ALCP-total after correcting for multiple testing [24].