Chunk #33 — Materials and Methods — Adjustments for Multiple Comparisons

Source

A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.

Embedded

yes

Text

We assessed genome-wide significance with a Bonferroni correction (p cutoff = 1.013×10−7 considering 493,609 independent tests in the Bergen cohort (see Text S1), 100 tests in the ICGN cohort, 7 tests in the NETT/NAS study and 6 tests in the BEOCOPD study (Total 493,772 tests).