These associations were sustained in sensitivity analyses controlling for benzodiazepines (positive control,) and statins (negative control) (eFigure in the Supplement), with univariate distributions of benzodiazepine and statin use (eTable 5 in the Supplement). The protective associations of buprenorphine and naltrexone were also sustained in analyses that limited events to those that occurred among individuals without a concurrent alcohol use disorder diagnosis (eFigure in the Supplement) and individuals with an active OUD diagnosis in the electronic medical record at the time of ED visit or hospitalization (eFigure in the Supplement).
