Chunk #0 — INTRODUCTION

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μ-Opioid receptor gene (OPRM1) polymorphism A118G: lack of association in Finnish populations with alcohol dependence or alcohol consumption.

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Alcohol dependence and alcohol abuse are complex disorders involving multiple genetic and environmental factors. Based on twin and adoption studies, the hereditary component of alcohol dependence has been estimated to be 50–60% (e.g. Heath et al., 1997).