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Chunk #53 — Results — Gene effects: candidate genes

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Heritability and molecular-genetic basis of resting EEG activity: a genome-wide association study.
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and the present study. Although all SNPs were imputed in our data, with a single exception imputation r2 values uniformly approached 1. Ten SNPs with nominally significant associations (p < .05) in previous studies and the present one are highlighted. In all, 18 SNPs in our data were associated with beta power at this level of significance. Substantial pairwise LD characterizes this region of the chromosome. Table 5 therefore includes the median LD statistic (r2) for each SNP in relation to all others. These values tend to be quite close to 1 for the majority of SNPs, suggesting a high level of dependency among them, and therefore that the nominally significant p-values represent a single signal.