mb and the MHC region at chr6:31–33 mb), while other regions showed fewer heritable genes (e.g., neuronal protocadherin gene cluster at chr5:140–141 mb and epidermal keratin gene clusters on chr17:39–40 mb and chr21:31–32 mb). Figure 1c shows that heritability is strongly associated with mean expression (r=0.356, P < 10−200), with a striking increase above an array-specific detection threshold, with detectable expression for 21,971 transcripts (50.3%).