paperKB
coga / coga-kb
Help
Sign in

Chunk #6 — Methods — Data simulation

Source
A comparison of multivariate genome-wide association methods.
Embedded
yes

Text

Genotype data were simulated for one bi-allelic quantitative trait locus (QTL) with minor allele frequency q and major allele frequency p. Genotypes were generated by sampling two alleles independently from a binomial distribution as 0 or 1, using two trials and a probability of success of each trial equal to q. The genotype is the sum of the two alleles, which can be 0, 1 or 2. Because alleles were sampled independently, genotypes were in Hardy Weinberg equilibrium.