for the autism risk gene neuroligin-3 (NLGN3), which are reduced in mice exposed to VPA, were associated with gamma phase locking in mice as well. Thus, this study suggests the possibility that an autism endophenotype may be related to an autism risk gene through a specific mechanism (gamma phase locking), which would help to understand the gene function reflected in the mediating mechanism as well as the specific nature of the genetic risk conveyed by the candidate gene and candidate endophenotype.
