Although previous studies have reported variation in beta EEG among individuals diagnosed with AD and related conditions, there have been relatively few studies examining genetic variants in relation to beta EEG and only one finding that has been replicated to date (GABRA212,26,57). Subsequently, associations between GABRA2, AD25,58–62 drug dependence58,63 and externalizing behavior64–67 have been observed, indicating the utility of beta EEG as an endophenotype for facilitating discovery of genes underlying disinhibitory behavior.
