In addition to the parent with the GRM5 variant, we were able to obtain ADHD Self-Report Scales for an additional 20 parents with CNVs overlapping any of the 22 top candidate genes from Table 2 (presented in Supplementary Table S5). Two parents (for genes IMMP2L and A2BP1) met definitive criteria for adulthood ADHD (score of 24 and above on either section A or section B of the ASRS) and three parents (for genes A2BP1, DPP6 and PTPRD) were likely to meet criteria (ASRS score 17–23 on either section). However, interpretation of this data is complex owing to our limited knowledge of adult ADHD and its relationship to the childhood form.
