Chunk #4 — Results — Cis- and trans-eQTL mapping

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Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA.

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Results of a genome-wide eQTL analysis on 289,044 common SNPs, present on the Illumina HumanHap300 platform in peripheral blood expression data of 1,469 unrelated individuals, are provided in Table 1, Table S1, Table S2, Figure S1 (controlling false discovery rate (FDR) at 0.05 using a permutation strategy).