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Chunk #8 — Introduction

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Adolescent but not adult rats exhibit ethanol-mediated appetitive second-order conditioning.
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and a relatively high (2.0 g/kg) ethanol dose. Within each dose there was systematic variation of postadministration time interval (either 5-20 min or 30-45 min after ethanol administration). These post-administration times were chosen on the basis of previous research indicating that, in preweanling rats, a 5 min delay between intragastric ethanol administration and the taste CS results in second-order conditioned place preference, while place aversions are more likely to be observed when exposure to the CS is delayed until 30 min following drug intubation (Molina et al., 2006; 2007).