Recent studies have used source localization methods, such as exact low-resolution brain electromagnetic tomography (eLORETA) [22], to compute functional connectivity, a measure of temporal synchrony or correlation between signals of two or more spatially separated brain regions, representing functional integration between these areas [23]. These studies use lagged connectivity [24] to overcome volume conduction artifacts [23,25]. While the eLORETA-based functional connectivity method has been utilized to study cognitive functioning in neuropsychiatric disorders [23,26,27,28,29], very few studies have utilized these approaches to investigate AUD [30] and none have examined alcohol-induced neurocognitive outcomes, such as memory problems. Since the default mode network supports memory functions [31,32,33,34], we employed functional connectivity across the default mode network regions to examine alcohol-induced memory problems.
