significantly lower genetic coverage (78%) than previously reported (90%) (electronic database: http://www.cidr.jhmi.edu/download/HumanHap650Y_info.pdf). Finally, in comparing whether more samples or more SNPs enhanced power most dramatically, we found that a modest increase in sample size (19%) had a more profound impact on the power to detect gene expression associations (a 21% increase in this case) than increasing the genetic coverage. These power and genetic coverage issues are fully detailed in a separate report [49].
