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Chunk #17 — 2. Method — 2.4. Statistical and bioinformatics analysis of microarray data

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Changes in gene expression within the extended amygdala following binge-like alcohol drinking by adolescent alcohol-preferring (P) rats.
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Genes differentially expressed at FDR = 0.2 were uploaded into Ingenuity Pathway Analysis (Ingenuity Systems, www.ingenuity.com). Genes were identified by their Affymetrix probe set id and then mapped to their corresponding objects in the Ingenuity® Knowledge Base. These molecules, called Network Eligible molecules, were overlaid onto a global molecular network developed from information contained in the Ingenuity Knowledge Base. Networks of Network Eligible Molecules were then algorithmically generated based on their connectivity.