Genes differentially expressed at FDR = 0.2 were uploaded into Ingenuity Pathway Analysis (Ingenuity Systems, www.ingenuity.com). Genes were identified by their Affymetrix probe set id and then mapped to their corresponding objects in the Ingenuity® Knowledge Base. These molecules, called Network Eligible molecules, were overlaid onto a global molecular network developed from information contained in the Ingenuity Knowledge Base. Networks of Network Eligible Molecules were then algorithmically generated based on their connectivity.