Chunk #25 — Model — Genotypic Values — Single Locus with Arbitrary Dominance

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Data and theory point to mainly additive genetic variance for complex traits.

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For the ‘U’-distribution, assuming N is large, and ignoring terms of O(1/N), the integrals simplify to E(V A)∼(a 2+d 2/3)/K, E(V D)∼d 2/(3K) and E(V A)/E(V G) = 1−d 2/(3a 2+2d 2).