Three hundred forty-nine microsatellite markers were genotyped on these families. Twenty-four additional markers included in the fine-mapping subsequent to the initial genome scan. In the initial analyses a LOD score of 2.25 for marker D9S288 on chromosome 9p was observed. However, after finemapping the LOD score dropped to 1.97. In general, LOD scores above 3.6 are considered to be genome-wide significant.
