The French sample comprised 308 patients with BD (129 men and 179 women; mean age at interview 43.25 ± 12.6 years old; 229 BD type I, 76 BD type II and 3 BD type NOS). All patients completed the CTQ. Three hundred patients were successfully genotyped for the l/s variant (5HTTLPR) and for the rs25531 (8 DNA failed to be amplified by PCR). The SLC6A4 promoter variants genotypic frequencies were in Hardy-Weinberg equilibrium (p = 0.48).