CPM targets the pons and ACD affects the cerebellum. Total infratentorial volume (including pons, cerebellar hemispheres, vermis, fissures, cisterns, and fourth ventricle) is significantly smaller in uncomplicated alcoholics than control subjects. The volume of the pons (Chanraud et al. 2009b; Pfefferbaum et al. 2002b; Sullivan 2003) and cerebellum (i.e., hemispheres) (Boutte et al. 2012; Chanraud et al. 2007, 2009a; De Bellis et al. 2005; Sullivan et al. 2000a,c) is smaller in uncomplicated alcoholics than in normal controls. Alcoholism-related volume deficits are also prevalent in gray and white matter (Shear et al. 1996; Sullivan et al. 2003) of the cerebellar vermis (Antunez et al. 1998; Piguet et al. 2006; Sullivan et al. 2006b, 2010), predominately in anterior superior but not posterior inferior regions (Sullivan et al. 2000a) (see figure 6).
