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Chunk #25 — MATERIALS AND METHODS — Signal Recording and Processing — Calculation of movement-related PAC. — Fluctuations of movement-related PAC.

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Cross-frequency phase-amplitude coupling in repetitive movements in patients with Parkinson's disease.
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To estimate the fluctuation of PAC over time in different tasks, we calculated the coefficient of variance (CoV) of the movement-related PAC for each task and for each subject. CoV was calculated as the ratio of the standard deviation to the mean across 55 time points of averaged PAC for each subject.