Twin studies leverage the difference in the proportion of genes shared between MZ twins (who share 100% of their segregating genes) and dizygotic (DZ) twins (who share roughly 50% of their segregating genes) to estimate additive genetic (A), shared environmental (i.e. environmental factors that make twins similar to each other; C) and non-shared environmental (i.e. factors that make twins different from each other, including measurement error; E) contributions to a given phenotype. More information on twin studies is provided elsewhere (Plomin et al. 2012).