in the brain, which may result in both short- and long-term behavioral impairments. Specifically, youth with an alcohol use disorder show structural deficits in the hippocampus and prefrontal cortex compared to youth without an alcohol use disorder (De Bellis et al., 2000; Nagel et al. 2005; Medina et al., 2008). Given that these regions are central to emotion regulation, these deficits may heighten vulnerability for depression.
