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Chunk #2 — Introduction — Adult antisocial behavior (AAB)

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Unraveling the genetic etiology of adult antisocial behavior: a genome-wide association study.
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In the present study, we performed a genome-wide association test on a combined dataset, composed of phenotypic data from two cohorts. Adult antisocial behavior was measured by a diagnostic antisocial personality disorder (ASPD) and a non-diagnostic adult antisocial behavior questionnaire. Antisocial personality disorder (ASPD) is a mental health condition defined by the American Psychological Association (APA) as a disorder characterized by “…a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood” [9]. This definition emphatically includes an early start of maladaptive behavior and demands that the behavior is persistent. Evidence of conduct disorder with onset before the age of 15, is therefore stated as an essential condition for the diagnoses of ASPD. The prevalence of ASPD is higher in males (3%) than in females (1%) and shows a high co-morbidity with other psychiatric syndromes [10].