with MAF<0.05), HWE p<1E-06, and imputation info <0.4. For data generated with the Illumina Human Core Exome BeadChip the SNP exclusion criteria were otherwise identical, except that a threshold of minor allele count <2 was applied instead of a MAF cut-off. Further, the same sample quality thresholds as in post-genotyping quality control were applied. Quality controls and imputation for all Finnish GWAS data were done centrally at the Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland.
