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Chunk #30 — Comment — Limitations

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Familial influences on conduct disorder reflect 2 genetic factors and 1 shared environmental factor.
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Our findings can be usefully compared with results from recently completed parallel analyses with DSM-IV criteria for antisocial personality disorder.34 Using the same methods and sample, we found evidence for 2 genetic factors underlying the antisocial personality disorder criteria, labeled aggressive-disregard and disinhibition, but no shared environmental common factor. The aggressive-disregard factor—characterized by prominent loadings on criteria assessing fighting and reckless disregard— resembles our CD overt aggression genetic factor. The disinhibition factor—with stronger loadings on criteria reflecting failure to plan and being deceitful and irresponsible—bears some similarity to our rule-breaking genetic factor.