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Chunk #8 — INTRODUCTION — Description of the i-GSAE4GWAS web server — Input data

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i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study.
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The input data of i-GWAS are SNP data, mainly P-values. The server will transform the P-value to −log(P-value). Some other values of association test like odds ratio and statistics are also accepted. Here, we define all these input values as ‘association value’. The detailed format of input is a SNP list with two columns, namely SNP identifier and its corresponding association value. A gene list with gene HUGO symbol (http://www.genenames.org/) (18) and along with corresponding association value is also accepted but not recommended due to the limitation of gene variation as described above.