To allow a comprehensive and critical examination of the data, and to assist with planning future studies, we have listed the various association studies, with information about the specific addiction or related phenotype, the numbers of cases (or families) and controls, the specific genes analyzed, and the populations studied (Table 1). In Table 2 we provide the list of all the SNPs (sorted by rs number) that were reported to be associated with drug addiction in at least one study. For each SNP the specific addiction and the specific population in which the association was found (indicated under the specific addiction) are indicated. The references listed are all the studies that analyzed the specific SNP including the one/s that identified the association. In addition, we have listed all the SNPs that were analyzed and were not reported to be associated with drug addiction, along with the gene location and the relevant references (Supplement Table 1). In Supplement Table 2 we provide the allele frequencies of all the variants reported in this review in three HapMap populations: CEU (Utah residents with ancestry from northern and western Europe), YRI (Yoruba, Nigeria) and CHB (Han Chinese in Beijing, China).
