Chunk #12 — METHODS — Statistical analysis

Source: Hippocampal volumes in UK Biobank are associated with only in older adults.
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To formally assess the interaction between age and APOE status, we fit two linear regression models: Model 1 for the additive effects of APOE and age: Volume=β0+β1APOE+β2Age+∑i=3NβiCovariate+ε Model 2 for the interactive effects of APOE and age: Volume=β0+β1APOE+β2Age+β3APOE*Age+∑i=4NβiCovariate+ε