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Chunk #3 — Background

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Linkage analysis merging replicate phenotypes: an application to three quantitative phenotypes in two African samples.
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We note that in the process of simulation, recombination could occur only once per chromosome per meiosis and that this recombination could not occur within a gene. This allows us to refer to IBD at a particular gene. In real data, we would not have perfect information, although with extensive genotyping and sequencing we would be able to approach this. Recombination within a gene is also possible, although it is less likely than in the larger intergenic regions. Furthermore, a multipoint analysis is unnecessary because the single point information is completely informative.