Data for the first study were collected between 1996 and 2000, by a telephone psychiatric interview containing lifetime assessments of several psychiatric disorders including adult antisocial behavior. This study cohort includes 1649 (43% male) participants, age range 24–41 (M = 31.2, SD = 3.5) and makes use of a non-diagnostic construct to measure adult antisocial behavior. Subjects in the second cohort were drawn from a series of studies as part of a Tobacco and Alcohol project, of which data were collected between 1981 and 2000. Study cohort 2 includes 3167 (41% male) individuals, who were aged between 18 and 81 (M = 47.6 years, SD = 9.5), and utilizes a diagnostic measure of antisocial personality disorder as its construct. Phenotypic and genotypic data collection was approved by the Queensland Institute of Medical Research (QIMR) Ethics Committee and informed consent was obtained from all participants. Phenotypic data on antisocial behavior were collected retrospectively using a semi-structured interview, administered by telephone. The total sample comprised of all the individuals for whom we had both genotypic and phenotypic data. Yielding a final study sample comprised of 4816 individuals from 2227 independent families.
